79

2013

6.2

Maintenance of Databases and Acceleration of Programs

6.2

Cysteine - - Cysteine ... Cysteine - - Cysteine,

in the single-letter code then finally.

CXXC [3..5 X] CXXC.

He then compiled such signatures into the PROSITE signature database, but the pre­

cisely labelled protein sequences (according to their family membership, structure in

domains, sequence properties) as entries in the Swiss-Prot database. After some time, the

work became too much for one person, and so the PROSITE database was gradually cre­

ated. Around the turn of the millennium, it was concluded that protein labelling could no

longer be a single task for one country because of the ever-increasing number of sequences.

Together with the EBI in Cambridge and American scientists, the UniProt database was

founded.

6.2  Maintenance of Databases and Acceleration of Programs